Description
Product Name: | Acetyl-Histone H2B-K20 Polyclonal Antibody |
Product Code: | CAB24886 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, HeLa+TSA, NIH/3T3, NIH/3T3+TSA, C6, C6+TSA |
Cellular Location: | Chromosome, Nucleus |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.
Immunogen: | A synthetic acetylated peptide around K20 of human Histone H2B (NP_003519.1). |
Sequence: | Email for sequence |
Synonyms: | H2B, H2BE, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105, H2B-GL105, HIST2H2BE |
Calculated MW: | 14kDa |
Observed MW: | 17kDa |