ACER3 Antibody (PACO23793)
- SKU:
- PACO23793
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ACER3 Antibody (PACO23793) |
| Antibody SKU: | PACO23793 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human PHCA. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO cells, using PHCA antibody. |
 | Immunofluorescence analysis of MCF-7 cells, using PHCA antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human placenta tissue using PHCA antibody. |
| Background: | Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. |
| Synonyms: | Alkaline phytoceramidase; Aphc; Alkaline ceramidase; EC 3.5.1.-; Alkaline dihydroceramidase SB89 |
| UniProt Protein Function: | ACER3: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. Belongs to the alkaline ceramidase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Hydrolase; EC 3.5.1.-; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 11q13.5 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to Golgi membrane Biological Process: ceramide metabolic process; positive regulation of cell proliferation; sphingolipid biosynthetic process; sphingolipid metabolic process; sphingosine biosynthetic process |
| UniProt Code: | Q9NUN7 |
| NCBI GenInfo Identifier: | 296439452 |
| NCBI Gene ID: | 55331 |
| NCBI Accession: | Q9NUN7.3 |
| UniProt Secondary Accession: | Q9NUN7,B2RC99, |
| UniProt Related Accession: | Q9NUN7 |
| Molecular Weight: | 15,895 Da |
| NCBI Full Name: | Alkaline ceramidase 3 |
| NCBI Synonym Full Names: | alkaline ceramidase 3 |
| NCBI Official Symbol: | ACER3 |
| NCBI Official Synonym Symbols: | APHC; PHCA |
| NCBI Protein Information: | alkaline ceramidase 3 |
| UniProt Protein Name: | Alkaline ceramidase 3 |
| UniProt Synonym Protein Names: | Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC |
| Protein Family: | Alkaline ceramidase |
| UniProt Gene Name: | ACER3 |
| UniProt Entry Name: | ACER3_HUMAN |
| Antibodies | ELISA Kits |
| ACER3 Antibody (PACO00406) | PHCA Colorimetric Cell-Based ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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