Description
| Antibody Name: | ACER3 Antibody |
| Antibody SKU: | PACO00406 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human APHC. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC |
| UniProt Protein Function: | ACER3: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. Belongs to the alkaline ceramidase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Hydrolase; EC 3.5.1.-; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 11q13.5 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to Golgi membrane Biological Process: ceramide metabolic process; positive regulation of cell proliferation; sphingolipid biosynthetic process; sphingolipid metabolic process; sphingosine biosynthetic process |
| UniProt Code: | Q9NUN7 |
| NCBI GenInfo Identifier: | 296439452 |
| NCBI Gene ID: | 55331 |
| NCBI Accession: | Q9NUN7.3 |
| UniProt Secondary Accession: | Q9NUN7,B2RC99, |
| UniProt Related Accession: | Q9NUN7 |
| Molecular Weight: | 15,895 Da |
| NCBI Full Name: | Alkaline ceramidase 3 |
| NCBI Synonym Full Names: | alkaline ceramidase 3 |
| NCBI Official Symbol: | ACER3 |
| NCBI Official Synonym Symbols: | APHC; PHCA |
| NCBI Protein Information: | alkaline ceramidase 3 |
| UniProt Protein Name: | Alkaline ceramidase 3 |
| UniProt Synonym Protein Names: | Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC |
| Protein Family: | Alkaline ceramidase |
| UniProt Gene Name: | ACER3 |
| UniProt Entry Name: | ACER3_HUMAN |