Description
Antibody Name: | ACER3 Antibody |
Antibody SKU: | PACO00406 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human APHC. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC |
UniProt Protein Function: | ACER3: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. Belongs to the alkaline ceramidase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Hydrolase; EC 3.5.1.-; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 11q13.5 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to Golgi membrane Biological Process: ceramide metabolic process; positive regulation of cell proliferation; sphingolipid biosynthetic process; sphingolipid metabolic process; sphingosine biosynthetic process |
UniProt Code: | Q9NUN7 |
NCBI GenInfo Identifier: | 296439452 |
NCBI Gene ID: | 55331 |
NCBI Accession: | Q9NUN7.3 |
UniProt Secondary Accession: | Q9NUN7,B2RC99, |
UniProt Related Accession: | Q9NUN7 |
Molecular Weight: | 15,895 Da |
NCBI Full Name: | Alkaline ceramidase 3 |
NCBI Synonym Full Names: | alkaline ceramidase 3 |
NCBI Official Symbol: | ACER3 |
NCBI Official Synonym Symbols: | APHC; PHCA |
NCBI Protein Information: | alkaline ceramidase 3 |
UniProt Protein Name: | Alkaline ceramidase 3 |
UniProt Synonym Protein Names: | Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC |
Protein Family: | Alkaline ceramidase |
UniProt Gene Name: | ACER3 |
UniProt Entry Name: | ACER3_HUMAN |