Description
| Product Name: | ACAT1 Monoclonal Antibody |
| Product Code: | CAB24607 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64028 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | PC-3, 293F, Mouse liver |
| Cellular Location: | Mitochondrion |
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 34-427 of human ACAT1(NM_000019.4). |
| Sequence: | VSKPT LKEVV IVSAT RTPIG SFLGS LSLLP ATKLG SIAIQ GAIEK AGIPK EEVKE AYMGN VLQGG EGQAP TRQAV LGAGL PISTP CTTIN KVCAS GMKAI MMASQ SLMCG HQDVM VAGGM ESMSN VPYVM NRGST PYGGV KLEDL IVKDG LTDVY NKIHM GSCAE NTAKK LNIAR NEQDA YAINS YTRSK AAWEA GKFGN EVIPV TVTVK GQPDV VVKED EEYKR VDFSK VPKLK TVFQK ENGTV TAANA STLND GAAAL VLMTA DAAKR LNVTP LARIV AFADA AVEPI DFPIA PVYAA SMVLK DVGLK KEDIA MWEVN EAFSL VVLAN IKMLE IDPQK VNING GAVSL GHPIG MSGAR IVGHL THALK QGEYG LASIC NGGGG ASAML IQKL |
| Synonyms: | T2, MAT, ACAT, THIL |
| Calculated MW: | 45kDa |
| Observed MW: | 42kDa |
![ACAT1 Monoclonal Antibody [PAT2C5A] (CPAB0463)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/58685/63867/acat1-monoclonal-antibody-pat2c5a-cpab0463__95386__45567.1706535183.jpg?c=1 "ACAT1 Monoclonal Antibody [PAT2C5A] (CPAB0463)")
