Name: ACAD8 Antibody (PACO42554)
SKU: PACO42554
Availability: OutOfStock

Antibody Name:	ACAD8 Antibody (PACO42554)
Antibody SKU:	PACO42554
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human Isobutyryl-CoA dehydrogenase, mitochondrial protein (201-415AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot. Positive WB detected in: Mouse liver tissue, Mouse heart tissue, Mouse skeletal muscle tissue. All lanes: ACAD8 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 46, 32, 39 kDa. Observed band size: 46, 39 kDa.
	Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO42554 at dilution of 1:100.

Background:	Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Plays a role in transcriptional coactivation within the ARC complex.
Synonyms:	Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8), ACAD8, ARC42 IBD

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:	This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]
UniProt Code:	Q9UKU7
NCBI GenInfo Identifier:	26006699
NCBI Gene ID:	27034
NCBI Accession:	Q9UKU7.1
UniProt Secondary Accession:	Q9UKU7
UniProt Related Accession:	Q9UKU7
Molecular Weight:	39kDa
NCBI Full Name:	Isobutyryl-CoA dehydrogenase, mitochondrial
NCBI Synonym Full Names:	acyl-CoA dehydrogenase family member 8
NCBI Official Symbol:	ACAD8
NCBI Official Synonym Symbols:	ARC42; ACAD-8
NCBI Protein Information:	isobutyryl-CoA dehydrogenase, mitochondrial
UniProt Protein Name:
UniProt Synonym Protein Names:
Protein Family:	Isobutyryl-CoA dehydrogenase
UniProt Gene Name:
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