Description
Antibody Name: | ABHD3 Antibody (PACO39202) |
Antibody SKU: | PACO39202 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phospholipase ABHD3 protein (52-309AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human lung tissue using PACO39202 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO39202 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids. |
Synonyms: | Phospholipase ABHD3 (EC 3.1.1.32) (EC 3.1.1.4) (Abhydrolase domain-containing protein 3), ABHD3 |
UniProt Protein Function: | ABHD3: a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]Protein type: EC 3.1.1.-; Membrane protein, integral; HydrolaseChromosomal Location of Human Ortholog: 18q11.2Cellular Component: plasma membraneMolecular Function: phospholipase A1 activity; phospholipase A2 activityBiological Process: phosphatidylcholine biosynthetic process; phosphatidylcholine metabolic process |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8WU67 |
NCBI GenInfo Identifier: | 134035377 |
NCBI Gene ID: | 171586 |
NCBI Accession: | Q8WU67.2 |
UniProt Secondary Accession: | Q8WU67,O43411, B0YIV0, B7Z5C2 |
UniProt Related Accession: | Q8WU67 |
Molecular Weight: | 15,525 Da |
NCBI Full Name: | Phospholipase ABHD3 |
NCBI Synonym Full Names: | abhydrolase domain containing 3 |
NCBI Official Symbol: | ABHD3 |
NCBI Official Synonym Symbols: | LABH3 |
NCBI Protein Information: | phospholipase ABHD3 |
UniProt Protein Name: | Phospholipase ABHD3 |
UniProt Synonym Protein Names: | Abhydrolase domain-containing protein 3Curated |
Protein Family: | Phospholipase |
UniProt Gene Name: | ABHD3 |
UniProt Entry Name: | ABHD3_HUMAN |