Description
| Antibody Name: | ABCC12 Antibody (PACO18497) |
| Antibody SKU: | PACO18497 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human ABCC12 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18497(ABCC12 Antibody) at dilution 1/10, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. |
| Synonyms: | ATP-binding cassette, sub-family C (CFTR/MRP), member 12 |
| UniProt Protein Function: | ABCC12: Probable transporter. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter Chromosomal Location of Human Ortholog: 16q12.1 |
| NCBI Summary: | This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96J65 |
| NCBI GenInfo Identifier: | 161788999 |
| NCBI Gene ID: | 94160 |
| NCBI Accession: | Q96J65.2 |
| UniProt Secondary Accession: | Q96J65,Q49AL2, Q8TAF0, Q8TEY2, |
| UniProt Related Accession: | Q96J65 |
| Molecular Weight: | 104,660 Da |
| NCBI Full Name: | Multidrug resistance-associated protein 9 |
| NCBI Synonym Full Names: | ATP binding cassette subfamily C member 12 |
| NCBI Official Symbol: | ABCC12 |
| NCBI Official Synonym Symbols: | MRP9 |
| NCBI Protein Information: | multidrug resistance-associated protein 9 |
| UniProt Protein Name: | Multidrug resistance-associated protein 9 |
| UniProt Synonym Protein Names: | ATP-binding cassette sub-family C member 12 |
| Protein Family: | ABC transporter C family |
| UniProt Gene Name: | ABCC12 |
| UniProt Entry Name: | MRP9_HUMAN |
| Antibodies | ELISA Kits |
| ABCC12 Antibody (PACO00354) | Human MRP9 / ABCC12 ELISA Kit |
| Human Multidrug resistance-associated protein 9 (ABCC12) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
