Description
Product Name: | ABCB6 Polyclonal Antibody |
Product Code: | CAB8880 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:200-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Cell membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Mitochondrion outer membrane, Multi-pass membrane protein |
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 642-842 of human ABCB6 (NP_005680.1). |
Sequence: | ISSGC IRIDG QDISQ VTQAS LRSHI GVVPQ DTVLF NDTIA DNIRY GRVTA GNDEV EAAAQ AAGIH DAIMA FPEGY RTQVG ERGLK LSGGE KQRVA IARTI LKAPG IILLD EATSA LDTSN ERAIQ ASLAK VCANR TTIVV AHRLS TVVNA DQILV IKDGC IVERG RHEAL LSRGG VYADM WQLQQ GQEET SEDTK PQTME R |
Synonyms: | ABC, LAN, PRP, umat, MTABC3 |
Calculated MW: | 94kDa |
Observed MW: | Refer to figures |