Description
Antibody Name: | ABCA9 Antibody (PACO37730) |
Antibody SKU: | PACO37730 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human ATP-binding cassette sub-family A member 9 protein (106-220AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of Hela cells using PACO37730 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May play a role in monocyte differentiation and lipid homeostasis. |
Synonyms: | ATP-binding cassette sub-family A member 9, ABCA9 |
UniProt Protein Function: | ABCA9: May play a role in monocyte differentiation and lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Transporter, ABC family; Transporter; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q24.2Cellular Component: mitochondrion; integral to membraneMolecular Function: transporter activity; ATPase activity; ATP bindingBiological Process: metabolic process; transport |
UniProt Protein Details: | |
NCBI Summary: | This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IUA7 |
NCBI GenInfo Identifier: | 27477115 |
NCBI Gene ID: | 10350 |
NCBI Accession: | NP_525022.2 |
UniProt Secondary Accession: | Q8IUA7,Q6P655, Q8N2S4, Q8WWZ5, Q96MD8 |
UniProt Related Accession: | Q8IUA7 |
Molecular Weight: | 30,998 Da |
NCBI Full Name: | ATP-binding cassette sub-family A member 9 |
NCBI Synonym Full Names: | ATP-binding cassette, sub-family A (ABC1), member 9 |
NCBI Official Symbol: | ABCA9 |
NCBI Official Synonym Symbols: | EST640918 |
NCBI Protein Information: | ATP-binding cassette sub-family A member 9; ATP-binding cassette A9 |
UniProt Protein Name: | ATP-binding cassette sub-family A member 9 |
UniProt Synonym Protein Names: | |
Protein Family: | ABC transporter A family |
UniProt Gene Name: | ABCA9 |
UniProt Entry Name: | ABCA9_HUMAN |