ABCA5 Antibody (PACO50862)
- SKU:
- PACO50862
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ABCA5 Antibody (PACO50862) |
| Antibody SKU: | PACO50862 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO50862 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO50862 at dilution of 1:100. |
| Background: | May play a role in the processing of autolysosomes. |
| Synonyms: | ATP-binding cassette sub-family A member 5, ABCA5, KIAA1888 |
| UniProt Protein Function: | ABCA5: May play a role in the processing of autolysosomes. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter; Transporter, ABC family; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17q24.3Cellular Component: Golgi membrane; lysosome; late endosome membrane; lysosomal membrane; late endosome; integral to membraneMolecular Function: transporter activity; ATPase activity; ATP bindingBiological Process: reverse cholesterol transport; metabolic process; cholesterol efflux |
| UniProt Protein Details: | |
| NCBI Summary: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WWZ7 |
| NCBI GenInfo Identifier: | 27262626 |
| NCBI Gene ID: | 23461 |
| NCBI Accession: | NP_758424.1 |
| UniProt Secondary Accession: | Q8WWZ7,Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14 |
| UniProt Related Accession: | Q8WWZ7 |
| Molecular Weight: | 99,273 Da |
| NCBI Full Name: | ATP-binding cassette sub-family A member 5 |
| NCBI Synonym Full Names: | ATP-binding cassette, sub-family A (ABC1), member 5 |
| NCBI Official Symbol: | ABCA5 |
| NCBI Official Synonym Symbols: | ABC13; EST90625 |
| NCBI Protein Information: | ATP-binding cassette sub-family A member 5; ATP-binding cassette A5 |
| UniProt Protein Name: | ATP-binding cassette sub-family A member 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | ABC transporter A family |
| UniProt Gene Name: | ABCA5 |
| UniProt Entry Name: | ABCA5_HUMAN |
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