AASS Polyclonal Antibody
- SKU:
- CAB24544
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | AASS Polyclonal Antibody |
| Product Code: | CAB24544 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat kidney |
| Cellular Location: | Mitochondrion |
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-600 of human AASS (NP_005754.2). |
| Sequence: | RRKVL VLGSG YISEP VLEYL SRDGN IEITV GSDMK NQIEQ LGKKY NINPV SMDIC KQEEK LGFLV AKQDL VISLL PYVLH PLVAK ACITN KVNMV TASYI TPALK ELEKS VEDAG ITIIG E |
| Synonyms: | AASS, LKR/SDH, LKRSDH, LORSDH, aminoadipate-semialdehyde synthase |
| Calculated MW: | 102kDa |
| Observed MW: | 102kDa |
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