AARSD1 Antibody (PACO00350)
- SKU:
- PACO00350
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AARSD1 Antibody |
| Antibody SKU: | PACO00350 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human AARSD1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | AARSD1; Alanyl-tRNA editing protein Aarsd1; Alanyl-tRNA synthetase domain-containing protein 1 |
| UniProt Protein Function: | AARSD1: Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: LigaseChromosomal Location of Human Ortholog: 17q21.31Cellular Component: cytoplasm; nucleusMolecular Function: protein binding; nucleic acid binding; metal ion binding; ATP binding; alanine-tRNA ligase activityBiological Process: regulation of translational fidelity; alanyl-tRNA aminoacylation |
| UniProt Protein Details: | |
| NCBI Summary: | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Code: | Q9BTE6 |
| NCBI GenInfo Identifier: | 31657223 |
| NCBI Gene ID: | 2888 |
| NCBI Accession: | BC053559 |
| UniProt Secondary Accession: | Q9BTE6,Q7Z6I1, B7Z7F9 |
| UniProt Related Accession: | Q9BTE6,Q14449 |
| Molecular Weight: | 51,946 Da |
| NCBI Full Name: | Homo sapiens growth factor receptor-bound protein 14, mRNA |
| NCBI Synonym Full Names: | growth factor receptor bound protein 14 |
| NCBI Official Symbol: | GRB14 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | growth factor receptor-bound protein 14 |
| UniProt Protein Name: | Alanyl-tRNA editing protein Aarsd1 |
| UniProt Synonym Protein Names: | Alanyl-tRNA synthetase domain-containing protein 1 |
| Protein Family: | Growth factor receptor-bound protein |
| UniProt Gene Name: | AARSD1 |
| UniProt Entry Name: | AASD1_HUMAN |
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