Description
Antibody Name: | AAGAB Antibody (PACO54134) |
Antibody SKU: | PACO54134 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Alpha- and gamma-adaptin-binding protein p34 protein (191-315AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human spleen tissue using PACO54134 at dilution of 1:100. |
![]() | Immunofluorescent analysis of A549 cells using PACO54134 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO54134 at dilution of 1:100. |
Background: | May be involved in endocytic recycling of growth factor receptors such as EGFR. |
Synonyms: | Alpha- and gamma-adaptin-binding protein p34, AAGAB |
UniProt Protein Function: | May be involved in endocytic recycling of growth factor receptors such as EGFR. |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q6PD74 |
NCBI GenInfo Identifier: | 153251315 |
NCBI Gene ID: | 79719 |
NCBI Accession: | NP_078942 |
UniProt Secondary Accession: | Q6PD74,Q6FI86, Q7Z5X9, Q9H0P1, Q9HAK0, B4DG44 |
UniProt Related Accession: | Q6PD74 |
Molecular Weight: | 36.7kDa (335aa), confirmed by MALDI-TOF |
NCBI Full Name: | alpha- and gamma-adaptin-binding protein p34 isoform 1 |
NCBI Synonym Full Names: | alpha and gamma adaptin binding protein |
NCBI Official Symbol: | AAGAB |
NCBI Official Synonym Symbols: | p34; KPPP1; PPKP1; PPKP1A |
NCBI Protein Information: | alpha- and gamma-adaptin-binding protein p34 |
UniProt Protein Name: | Alpha- and gamma-adaptin-binding protein p34 |
UniProt Synonym Protein Names: | |
Protein Family: | Alpha- and gamma-adaptin-binding protein |
UniProt Gene Name: | AAGAB |
UniProt Entry Name: |