14-3-3 gamma Polyclonal Antibody
- SKU:
- CAB21651
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | 14-3-3 gamma Polyclonal Antibody |
| Product Code: | CAB21651 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human 14-3-3 gamma (P61981). |
| Sequence: | VLSLL DNYLI KNCSE TQYES KVFYL KMKGD YYRYL AEVAT GEKRA TVVES SEKAY SEAHE ISKEH MQPTH PIRLG LALNY SVFYY EIQNA PEQAC HLAKT A |
| Synonyms: | DEE56, EIEE56, PPP1R170, 14-3-3GAMMA |
| Calculated MW: | 28kDa |
| Observed MW: | Refer to figures |
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